The UK-wide double-blind sham-controlled clinical trial of the Neupulse device for suppressing tics in Tourette syndrome run by Neupulse, Nottinghamshire Healthcare NHS Foundation Trust and the University of Nottingham showed that people who received active stimulation experienced a significant reduction in the severity and frequency of their tics. On average they saw a reduction in tic frequency of more than 25% while they received stimulation.
After using the device for 4 weeks, people who received active stimulation experienced a reduction in their tic severity of more than 35%. In total 59% of the people who received active stimulation experienced a reduction in tic severity of at least 25% compared to baseline.